The high level requirements for this work package were to design and provide a central point of storage of and access to all collected in-life, physiological endpoint, transcriptomic, proteomic and metabonomic raw and processed data, annotation and results arising from the InnoMed project.
The resulting integrated database schema models the standard process of experimental design and data collection, thus relating the heterogeneous data, most from different technologies, to common samples and animals. Powerful cross-technology querying allows fast access to clinical chemistry data relevant to specific Affymetrix arrays, or serum metabonomic data related to specific organ transcriptomic data, among others.
This lays the foundation for efficient cross-omic data analysis at all levels; investigation of two-compartment models and ultimately a systems view of toxicology.
All data generated by participating sites and laboratories are submitted to the hosting site (Genedata AG) located in Basel, Switzerland to undergo curation and pre-processing.
To consortium members, access to the database is made possible via a web portal that went live in June 2006.
To date, the database has received about 80% of the expected data.
Innomed PredTox Database: Central point of access to all subject-derived data (currently ~1.3 TB)
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