- Systems Toxicology, a merger between toxicology and “omics”, to predict toxicity earlier in drug development.
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Jochen König
Drug Discovery & Development magazine, August 01, 2008
- The InnoMed PredTox project - Current Status and Genedata Contribution
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Jochen König
Japanese SOT Annual Meeting, June 26, 2008
- The EU-FP6 PredTox Project - Using an Integrated Omics Approach to Mechanistic Biomarker Identification
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H. Ellinger-Ziegelbauer
ICCA workshop, June 11, 2008
- Absolute Protein Quantification in the Context of Non-Clinical Drug Safety Evaluation
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Ben C. Collins, Ning Tang, Peter J. Stone, Thomas Y. Lau, Albrecht Gruhler, Jean-Charles Gautier, William M. Gallagher, Stephen R. Pennington
American Society for Mass Spectrometry (ASMS) Conference on Mass Spectrometry and Allied Topics, Denver, USA, June 1 - 5, 2008
Poster from ASMS conference, June 2008
(1MB)
- Discovery and Identification of Markers of Toxicity in a Multi-Site, Multi-Compound Study: Selected Results from the EU PredTox Consortium
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Diane McCarthy, Ben Collins, Alexandra Walijew, Jean-Charles Gautier
ASMS annual meeting, Denver, Mai 31, 2008
- Creation of a Digital Slide and Tissue Microarray Resource from a Multi-Institutional Predictive Toxicology Study in the Rat: An Initial Report from the InnoMed PredTox Group
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Laoighse Mulrane, Elton Rexhepaj, Valerie Smart, John J. Callanan, Diclehan Orhan, Türkan Eldem, Angela Mally, Susanne Schroeder, Kirstin Meyer, Maria Wendt, Donal O’Shea, and William M. Gallagher
Experimental and Toxicological Pathology, Mai 13, 2008
- InnoMed PredTox Roundtable
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Friedlieb Pfannkuch
SOT Annual Meeting, Seattle, March 16-20, 2008
EU FP6 PredTox Project
(426KB)
- An integrated –omics approach towards a better understanding of drug-induced nephrotoxicity and useful biomarkers
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Frank Staedtler
SOT Annual Meeting, Seattle, March 16-20, 2008
Drug-Induced Nephrotoxicity and Useful Biomarkers
(509KB)
- The value of -omics in hepatotoxicity prediction
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Angela Mally
SOT Annual Meeting, Seattle, March 16-20, 2008
Omics in Hepatotoxicity Prediction
(1MB)
- Integrated transcriptomic and proteomic evaluation of gentamicin nephrotoxicity in rats
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E. Com, E. Boitier, J.P. Marchandeau, M. Courcol, J.F. Leonard, M. Duchesne, B. Genet, S. Schroeder, M. Wendt and J.C. Gautier
SOT Annual Meeting, Seattle, March 16-20, 2008
Gentamicin nephrotoxicity in rats
(367KB)
- Discovery of Markers Associated with Bile Duct Damage in Rat Plasma
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Diane McCarthy, Bio-Rad
SOT Annual Meeting, Seattle, March 16-20, 2008
Discovery of Markers Associated with Bile Duct Damage in Rat Plasma
(390KB)
- Application of a systems toxicology approach to investigate troglitazone hepatotoxicity in the rat
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E.R. Troesken, A. Gruhler, E. Boitier, Marchandeau, K. Arnold, B. Bidlingmaier, A. Brandenburg, M.Kurz, A. Pfenninger, J. Schnieders, I. Stammberger, M. Stolte, and A. Amberg
SOT Annual Meeting, Seattle, March 16-20, 2008
Troglitazone hepatotoxicity in the rat
(1MB)
- Improved Characterization and Interpretation of Toxicological Findings by Combining Omics Technologies with Conventional Endpoints
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M. Raschke, B. Riefke, A.-L. Frisk, S. Gründemann, T. Steger-Hartmann, H. Schweinfurth and K. Meyer
Deutsche Gesellschaft für Experimentelle und Klinische Pharmakologie und Toxikologie (DGPT) Annual Meeting, March 11, 2008
- Predictive Toxicology – an Integrated Project within the “Innovative Medicines for Europe Initiative“
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P. Hewitt
Predictive Human Toxicity and ADME/Tox Studies, Brussels, January 28, 2008
- InnoMed PredTox presents analysis results from systems toxicology studies
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Jochen König
Online Distribution, January 22, 2008