Links

ACute Tox
Optimization and pre-validation of an in vitro test strategy for predicting human acute toxicity

BioCop
BioCop aims at developing new bioassays for the rapid and easy screening of foodstuffs for selected pesticides, heavy metals, natural toxins produced by shellfish and fungi, therapeutic drugs and endocrine disrupters.
FOOD-CT-2005-006988

C-Path PSTC
The Predictive Safety Testing Consortium (PSTC) brings pharmaceutical companies together to share and validate each other’s safety testing methods under advisement of the FDA. The 16 corporate members of the consortium have begun sharing internally developed pre-clinical safety biomarkers in four workgroups: carcinogenicity, kidney, liver and vascular injury.

Carcinogenomics
Aim of the European Commission project CarcinoGenomics is to develop in vitro methods for assessing the carcinogenic potential of compounds.
LSHB-CT-2006-037712

ILSI-HESI
The mission of HESI’s Genomics Committee is to advance the scientific basis for the development and application of genomic methodologies to mechanism-based risk assessment; to address scientific issues relating to the use of these new technologies as a means for understanding toxic response and mechanisms; and to provide a scientific forum for a consensus-based approach to interpreting and applying these data.

NewGeneris
NewGeneris is an integrated EU project, with the objective to investigate the role of prenatal and early-life exposure to genotoxic chemicals present in food and the environment.
FOOD-CT-2005 016320

NHR DEV TOX
A prospective analysis of the mechanisms of nuclear hormone receptors and their potential as tools for the assessment of developmental toxicity

NSMF
NSMF (New Safe Medicines Faster) is an initiative aimed at improving drug development and approval in Europe by cooperation between public and private institutions.

Predictomics
Short-term in-vitro assays for predicting long-term toxicity

PROLIGEN
The PROLIGEN consortium studies the regenerative capacity of injured kidneys, using information derived from genomics, proteomics, and functional genomics.
LSHB-CT-2006-036813

ReProTect
Development of a novel approach in hazard and risk assessment for reproductive toxicity by a combination and application of in vitro, tissue and sensor technologies

Toxdrop
Highly parallel cell culture in nanodrops, a new format for high content cell based toxicity screening on Cell on Chips

U.S. Environmental Protection Agency (EPA) ToxCAST
The ToxCast™ Program for Prioritizing Toxicity Testing of Environmental Chemicals aims to develop the ability to forecast toxicity based on bioactivity profiling and, ultimately, to develop methods of prioritizing chemicals for further screening and testing to assist EPA in the management and regulation of environmental contaminants.