Links

ACute Tox
Optimization and pre-validation of an in vitro test strategy for predicting human acute toxicity

BioCop
BioCop aims at developing new bioassays for the rapid and easy screening of foodstuffs for selected pesticides, heavy metals, natural toxins produced by shellfish and fungi, therapeutic drugs and endocrine disrupters.
FOOD-CT-2005-006988

Carcinogenomics
Aim of the European Commission project CarcinoGenomics is to develop in vitro methods for assessing the carcinogenic potential of compounds.
LSHB-CT-2006-037712

NewGeneris
NewGeneris is an integrated EU project, with the objective to investigate the role of prenatal and early-life exposure to genotoxic chemicals present in food and the environment.
FOOD-CT-2005 016320

NHR DEV TOX
A prospective analysis of the mechanisms of nuclear hormone receptors and their potential as tools for the assessment of developmental toxicity

Predictomics
Short-term in-vitro assays for predicting long-term toxicity

PROLIGEN
The PROLIGEN consortium studies the regenerative capacity of injured kidneys, using information derived from genomics, proteomics, and functional genomics.
LSHB-CT-2006-036813

ReProTect
Development of a novel approach in hazard and risk assessment for reproductive toxicity by a combination and application of in vitro, tissue and sensor technologies

Toxdrop
Highly parallel cell culture in nanodrops, a new format for high content cell based toxicity screening on Cell on Chips

CHEMOFLUXOME Development of metabolomics and fluxomics methods for metabolic drug target and toxicity elucidation using yeast

NSMF
NSMF (New Safe Medicines Faster) is an initiative aimed at improving drug development and approval in Europe by cooperation between public and private institutions.

C-Path PSTC
The Predictive Safety Testing Consortium (PSTC) brings pharmaceutical companies together to share and validate each other’s safety testing methods under advisement of the FDA. The 16 corporate members of the consortium have begun sharing internally developed pre-clinical safety biomarkers in four workgroups: carcinogenicity, kidney, liver and vascular injury.

ILSI-HESI
The mission of the HESI Biomarkers Technical Committee is to advance the scientific basis for the development and application of biomarkers of target organ toxicity; to develop a systematic approach for the evaluation of biomarkers that bridge from the pre-clinical to clinical stages of drug development; and to provide a scientific forum for building consensus regarding how to apply biomarkers of toxicity in risk assessment.

U.S. Environmental Protection Agency (EPA) ToxCAST
The ToxCast™ Program for Prioritizing Toxicity Testing of Environmental Chemicals aims to develop the ability to forecast toxicity based on bioactivity profiling and, ultimately, to develop methods of prioritizing chemicals for further screening and testing to assist EPA in the management and regulation of environmental contaminants.

Toxicogenomics Project in Japan
The Toxicogenomics Project is a cooperative research project joining both the nation and private companies to create a toxicology database that enables both forward and reverse toxicology.